Ozone Therapy

What is Ozone?

Ozone (O3), a gas discovered in the mid-nineteenth century, is a molecule consisting of three atoms of oxygen in a dynamically unstable structure due to the presence of mesomeric states. The gas is colorless, acrid in odor and explosive in liquid or solid form. It has a half-life of 40 min at 20°C and about 140 min at 0°C. Its basic function is to protect humans from harmful effects of UV radiation.

History of Ozone Therapy

Ozone Therapy is the medical use of ozone for treating conditions. Ozone has been found to be an extremely safe medical therapy, free from side effects. In a 1980 study done by the German Medical Society for Ozone Therapy, 644 therapists were polled regarding their 384,775 patients, comprising a total of 5,579,238 ozone treatments administered. There were only 40 cases of side effects noted out of this number, which represents the incredibly low rate of .000007%, and only four fatalities. Ozone has thus proven to be the safest medical therapy ever devised. Considering that, at least 100,000 Americans a year die from drug reactions and interactions, ozone therapy is amazingly safe.

Mechanism of Action

Inactivation of bacteria, viruses, fungi, yeast, and protozoa: Ozone therapy disrupts the integrity of the bacterial cell envelope through oxidation of the phospholipids and lipoproteins. In fungi, O3 inhibits cell growth at certain stages. With viruses, the O3 damages the viral capsid and upsets the reproductive cycle by disrupting the virus-to-cell contact with peroxidation. The weak enzyme coatings on cells, which make them vulnerable to invasion by viruses, make them susceptible to oxidation and elimination from the body, which then replaces them with healthy cells.

Stimulation of oxygen metabolism:

Ozone therapy causes an increase in the red blood cell glycolysis rate. This leads to the stimulation of 2,3-diphosphoglycerate, which leads to an increase in the amount of oxygen released to the tissues. Ozone activates the Krebs cycle by enhancing oxidative carboxylation of pyruvate, stimulating the production of ATP. It also causes a significant reduction in NADH and helps to oxidize cytochrome C. There is a stimulation of production of enzymes, which act as free radical scavengers and cell-wall protectors: glutathione peroxidase, catalase, and superoxide dismutase. Production of prostacyclin, a vasodilator, is also induced by O3.

Intraarticular O3 therapy for pain control in osteoarthritis of the knee:

Ozone is being currently tested for its effectiveness in relieving the pain in patients suffering from osteoarthritis of the knee. The current status of the study is phase 2, which is sponsored by Ben-Gurion University of the Negev and the study being conducted by NCT00832312.


The Effect of Ozone Therapy for Lumbar-Herniated Disc:

Ozone is also being evaluated for its efficacy infiltration and its effectiveness in comparison with
microdiscectomy in the treatment of lumbar herniated disc with criteria for surgery. The study is currently in its phase 2 studies, which is sponsored by Kovacs Foundation and trials being carried out by NCT00566007. The study also evaluates the efficacy of infiltration in presence of corticoids, anesthetics, which is being compared by replacing O3 with oxygen.

Conditions that may benefit from treatment with Ozone Therapy include:

• Ozone Holistic Face and neck lift
• Meniscal tears and joint disorders
• Shingles (Herpes zoster) and Herpes Simplex
• Herniated Discs
• Diabetic ulcers and venous stasis
• Allergies & chronic sinusitis
• Lyme disease
• Alzheimer’s, senile dementia
• Autoimmune diseases
• Colitis and Crohn’s
• Vaginal infections
• Chronic hepatitis
• Chronic Fatigue Syndrome
• Candidiasis and many more conditions in simple words, it boosts the health, anti-aging, and well being of the patient. For this reason, it is suitable nearly for everyone who wants to restore health, rejuvenate the body or repair degeneration or an injury.

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